If you are seeing this error, try the following solutions in order: Check Antivirus Quarantine

Go to the game's page, select Properties , and click Verify files .

Scroll down to and click Add or remove exclusions .

Instead of wrestling with loader64.dll , consider these permanent solutions:

If you are seeing an error for (or the similar upc_r2_loader64.dll ) in Assassin's Creed Valhalla

Go to (not Google search results). Look for releases from established groups like EMPRESS or RUNE. Verify the hash (MD5/SHA256) of the loader64.dll against the crack’s NFO file. Never run a random DLL downloaded from a file-sharing forum.

If the file is missing and not in quarantine, the safest way to get it back is through the launcher: